Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MELKHLPKYKHITEHAETYANIDAGSLELFLSLFDISKKMNHVMEHYFAGRGLSEGKFKILMLLFDAKDHRLSPTELAKRSNVTKATITGLLDGLARDGFVSRRHHTEDKRKISIELTTEGKARLEQFLPGHFSKISAVMENYSDEEKDMFVKMLGDLFERLSVFKD 3VOD Chain:A ((21-111)) -----------------------------------VNQKKDRLLNEYLSPLDITAAQFKVLCSIRCAAC--ITPVELKKVLSVDLGALTRMLDRLVSKGWVERLPNPNDKRGVLVKLTTGGAAICEQC---------------------------------------

General information: TITO was launched using: RESULT: Template: 3VOD.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 297 -50552 -170.21 -555.52 target 2D structure prediction score : 0.70 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : -170.21 2D Compatibility (Sec. Struct. Predict.) : 0.70 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.416

(partial model without unconserved sides chains): PDB file : Tito_3VOD.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3VOD-query.scw PDB file : Tito_Scwrl_3VOD.pdb: