Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MFGKKQVLASVLLIPLLMTGCGVADQGEGRRDNNDVRNVNYRNPANDDMRNVNNRDNVDNNVNDNVNNNRVNDDNNNDRKLEVADEAADKVTDLKE-VKHADIIVAGNQAY--VAVVLTNGNKGAVENNLKKKIAKKV-----RSTDKNIDNVYVSANPDFVERMQGYGKRIQNGDPIAGLFDEFTQTVQRVFPNAE 2ZXQ Chain:A ((800-935)) ----------------------------------------------------------DNWTVSGSGKAEVEGDNNAMLRLTGKVDVSQRLTDLKAGQKYALYVGVDNRSTGDASVTVTSGGKVLATNSTGKSIAKNYIKAYGHNTNSNTEN-----GSSYFQNMYVFFTAPENGDATVTLSHKSTDGAHTYF----

General information: TITO was launched using: RESULT: Template: 2ZXQ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 617 6029 9.77 49.41 target 2D structure prediction score : 0.33 Monomeric hydrophicity matching model chain A : 0.67 3D Compatibility (PKB) : 9.77 2D Compatibility (Sec. Struct. Predict.) : 0.33 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.141

(partial model without unconserved sides chains): PDB file : Tito_2ZXQ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2ZXQ-query.scw PDB file : Tito_Scwrl_2ZXQ.pdb: