Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEQYSEACIEACIDCMKACNHCFTKCLEESVQHHLSGCIRLDRECADICALAVKAMQTDSPFMKEICALCADICEACGTECGKHDH-DHCQACAKACFTCAEQCRSMAA 5FJD Chain:A ((23-121)) ----SSHCVAVGEDCLR---HCFEMLAMNDAS--MGACTKATYDLVAACGALAKLAGTNSAFTPAFAKVVADVCAACKKECDKFPSIAECKACGEACQACAEECHKVA-

General information: TITO was launched using: RESULT: Template: 5FJD.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 404 -57702 -142.83 -588.79 target 2D structure prediction score : 0.82 Monomeric hydrophicity matching model chain A : 0.74 3D Compatibility (PKB) : -142.83 2D Compatibility (Sec. Struct. Predict.) : 0.82 1D Compatibility (Hydrophobicity) : 0.74 QMean score : 0.720

(partial model without unconserved sides chains): PDB file : Tito_5FJD.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5FJD-query.scw PDB file : Tito_Scwrl_5FJD.pdb: