Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNIEDLWDQFHQPLKTYI--SHRVNDQS--IVDDLLQIVFMKIQVHLPNLIDEQKIDSWIYRITRNTIIDFYRTKKTSEILPDVLHFNDSAEEENF----TKEATVCIRSTIKRLPEKYREALELTDFQGLSQKELSEKLGISYSGAKSRVQRGRGKLKQLLEGCCHIEADRYGNIVDFRILKE 2Q1Z Chain:A ((31-181)) ----ELFQHFAPKVKGFLMKSGSVASQAEECAQDVMATVWQKAHLFDPS---RASVATWIFTIARNRRIDGLRKDRQPE--PEDLFWGPDSEPDQADVYEMQQENARLGRAIARLPEAQRALIERAFFGDLTHRELAAETGLPLGTIKSRIRLALDRLRQ------------------------

General information: TITO was launched using: RESULT: Template: 2Q1Z.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 399 -12038 -30.17 -84.18 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain A : 0.71 3D Compatibility (PKB) : -30.17 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.71 QMean score : 0.418

(partial model without unconserved sides chains): PDB file : Tito_2Q1Z.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2Q1Z-query.scw PDB file : Tito_Scwrl_2Q1Z.pdb: