Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MQAAGHPEPLDSRGSFSLPTMGANVSQDNGTGHNATFSEPLPFLYVLLPAVYSGICAVGLTGNTAVILVILRAPKMKTVTNVFILNLAVADGLFTLVLPVNIAEHLLQYWPFGELLCKLVLAVDHYNIFSSIYFLAVMSVDRYLVVLATVRSRHMPWRTYRGAKVASLCVWLGVTVLVLPFFSFAGVYSNELQVPSCGLSFPWPEQVWFKASRVYTLVLGFVLPVCTICVLYTDLLRRLRAVRLRSGAKALGKARRKVTVLVLVVLAVCLLCWTPFHLASVVALTTDLP-QTPLVISMSYVITSLSYANSCLNPFLYAFLDDNFRKNFRSILRC 4N6H Chain:A ((124-410)) -------------------------------------------LAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKA--LDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAV-VCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRK

General information: TITO was launched using: RESULT: Template: 4N6H.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -257637 for 2222 contacts (-115.9/contact) + 2D Compatibility (PS) -28729 + (NN) -8761 + (LL) 812 1D Compatibility (HY) -36400 + (ID) 6150 Total energy: -336865.0 ( -151.60 by residue) QMean score : 0.320

(partial model without unconserved sides chains): PDB file : Tito_4N6H.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4N6H-query.scw PDB file : Tito_Scwrl_4N6H.pdb: