Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MGRWVNQSYTDGFFLLGIFSHSQTDLVLFSAVMVVFTVALCGNVLLIFLIYLDAGLHTPMYFFLSQLSLMDLMLVCNIVPKMAANFLSGRKSISFVGCGIQIGFFVSLVGSEGLLLGLMAYDRYVAVSHPLHYPILMNQRVCLQITGSSWAFGIIDGVIQMVAAMGLPYCGSRSVDHFFCEVQALLKLACADTSLFDTLLFACC-VFMLLLPFSIIMASYACILGAVLRIRSAQAWKKALATCSSHLTAVTLFYGAAMFMYLRPRRYRAPSHDKVASIFYTVLTPMLNPLIYSLRNGEVMGALRKGLDRCRIGSQH 4DKL Chain:A ((16-212)) -----------------------TAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALAD-ALATSTLPFQSVNYLMGTWPFGNILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIVNVCNWILS---------SAIGLPVMFMATTKYRQGSIDCTLTFS-HPTWYWENLLKICVFIFAFIMPVLIITVCYGLM---ILRLKSVRNIFEMLRIDEGLRLKIYKNTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQDVDAAVRGILRNAK

General information: TITO was launched using: RESULT: Template: 4DKL.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -156297 for 1317 contacts (-118.7/contact) + 2D Compatibility (PS) -19445 + (NN) -1977 + (LL) 2736 1D Compatibility (HY) -18000 + (ID) 2400 Total energy: -195383.0 ( -148.35 by residue) QMean score : 0.161

(partial model without unconserved sides chains): PDB file : Tito_4DKL.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4DKL-query.scw PDB file : Tito_Scwrl_4DKL.pdb: