Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTSNFSQPVVQLCYEDVNGSCIETPYSPGSRVILYTAFSFGSLLAVFGNLLVMTSVLHFKQLHSPTNFLIASLACADFLVGVTVMLFSMVRTVESCWYFGAKFCTLHSCCDVAFCYSSVLHLCFICIDRYIVVTDPLVYATKFTVSVSGICISVSWILPLTYSGAVFYTGVNDDGLEELVSALNCV---GGCQIIVSQGWVLIDFLL-FFIPTLVMIILYSKIFLIAKQQAIKIETTSSKVESSSESYKIRVAKRERKAAKTLGVTVLAFVISWLPYTVDILIDAFMGFLTPAYIYEICCWSAYYNSAMNPLIYALFYPWFRKAIKLILSGDVLKASSSTISLFLE 2Y01 Chain:A ((23-300)) ------------------------------------------LLIVAGNVLVIAAIGSTQRLQTLTNLFITSLACADLVVGLLVVPFGATLVVRGTWLWGSFLCELWTSLDVLCVTASIETLCVIAIDRYLAITSPFRYQSLMTRARAKVIICTVWAISALVS---FLPIMMHWWRDEDPQALKCYQDPGCCDFVTNRAYAIASSIISFYIPLLIMIFVALRVYREAKEQ------------SRV------MLMREHKALKTLGIIMGVFTLCWLPFFLVNIVNVFNRDLVPDWLFVAFNWLGYANSAMNPIIYCR-SPDFRKAFKRLLA----------------

General information: TITO was launched using: RESULT: Template: 2Y01.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -243712 for 1942 contacts (-125.5/contact) + 2D Compatibility (PS) -26172 + (NN) -1085 + (LL) 5020 1D Compatibility (HY) -24800 + (ID) 4600 Total energy: -295349.0 ( -152.08 by residue) QMean score : 0.346

(partial model without unconserved sides chains): PDB file : Tito_2Y01.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2Y01-query.scw PDB file : Tito_Scwrl_2Y01.pdb: