Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MFSNLYRGLLKTSSRFSDGVKSIFSAKKKLDQSLLDELEELLISMDIGHKTSKLIIDRLASIKFDKEV-EHNIITQQLMSEIEAILNPVVQPLILD-KNPHIIMVCGVNGNGKTTTIGKLAYKYKNMGKSVMLVACDTFRAAASEQLNIWAERSDCFIVTGEYGNDSASVAYRAVSQAIKGSVDVVLIDTAGRLQNNVNLMEELSKIYRTIKKLDGTAPHDVILVLDATTGQNAYSQLEAFSKMVSVTGLIITKLDGTAKGGVVIGLAETYRVKLHAIGIGESIEDLREFTSKEFAKALFGCD 2YHS Chain:A ((195-495)) FFARLKRSLLKTKENLGSGFISLFRGKKIDDDLFEELEEQLLIA-DVGVETTRKIITNLTEGASRKQLRDAEALYGLLKEEMGEILAKVDEPLNVEGKAPFVILMVGVNGVGKTTTIGKLARQFEQQGKSVMLAAGDTFRAAAVEQLQVWGQRNNIPVIAQHTGADSASVIFDAIQAAKARNIDVLIADTAGRLQNKSHLMEELKKIVRVMKKLDVEAPHEVMLTIDASTGQNAVSQAKLFHEAVGLTGITLTKLDGTAKGGVIFSVADQFGIPIRYIGVGERIEDLRPFKADDFIEALFAR-

General information: TITO was launched using: RESULT: Template: 2YHS.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -216058 for 2605 contacts (-82.9/contact) + 2D Compatibility (PS) -32612 + (NN) -15583 + (LL) 132 1D Compatibility (HY) -24400 + (ID) 7050 Total energy: -295571.0 ( -113.46 by residue) QMean score : 0.540

(partial model without unconserved sides chains): PDB file : Tito_2YHS.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2YHS-query.scw PDB file : Tito_Scwrl_2YHS.pdb: