Modeling by threading (Tito software)
Unconserved sides chains calculation (Scwrl software)
Evaluation (QMean software)
Input alignment information:
| Query sequence | MTAKEEEKQERFQLLMTQIGLQDVTTYEEFTKDAKIEKLVADKKNKTWQFHLHVPQIFPAALFHMMDVGMKRAFSQIAETEMQIVPENQTINETLIQDYWNLIVEPIGKQSPMIGKLLMEQKPTFKEPHFIEVAVHNDMEEATIQQRFQTKIIESYGKAGFPRLAMKMHMLDQSETDEYKAFAQAKQEEDQKKAAEAVQVMQKRQAEGQSGGGGAAPLTGPFQIGYKIKDDEEVKRLGDIYDEERRITVQGLIFATEIRELRSGRSLLQFKITDYTSSMIIKMFSRDNEDAAMFQNLKKGMWVKVRGSVQNDTFVRDLIMMAQDVNEIAGVKRLDTAEEKRAELHLHSPMSQMDATSSVDSLFKQAADWGHKAIAITDHSVAQSFPEAYGAGQKYGLKVIFGIEANLIDDGVPIAYNDQHIALEDATYCVFDVETTGLSAVYDTIIELAGVKMKNGEIIDKFEAFIDPGHPLSATTINLTGITDDMVKGSDPIDVVLKRFKEWSGDDILVAHNASFDMGFINTAYEKVGLEKAENAVVDTLELARFLYPHFKNHRLNTLTKKFNIILEQHHRAVFDAEATAYLAWKLIKDAKEMHNIDFHDSLNDYMGEGDAYKRARPFHATIYAQTAVGLKNLFKLITMS-NINYFYRVPRIPRSQLKKLREGLIIGTACSQGELFEAMMQKGMQAAEKVAEFYDFIEVQPKPVYAPLIERELVRDEKALEE-ILKNIVRVGEKTGKPVVATGNVHYKDPVDKIYRKILIHSQGG------ANPLNRAELPDVHFRTTDEMLKEFAFLGEEKAKEI-VVTNANLVVDWMENLKP--------IKDELYTPKIDGAEDEVRNMSYAMAHQLYGEKLPEIVEARLEKELKSIIGHGFAVIYLISHKLVKKSLVDGYLVG-SRGSVGSSFVATMTEITEVNPLPPHYLCPNCKDSEFFDDGSVGSGFDLPDKDCPHCGTAYQKEGQDIPFETFLGFKGDKVPDIDLNFSGDYQPVAHAYTKEIFGEDYVFRAGTIGTVAEKTA-----------FGYVRNYER----DMNMTIRGA-----------EIDRLVAGCT-------GVKRTTGQHPGGIIVIPDYMDVYDFTPVQFPADATDSEWK--TTHFDFHSI-HDNVLKLDILGHDDPTAIRMLQDLSG----------IDPKTIPTDDPDVMKLFGSTESLGVKPADIDSKTGTLGIPEFGTRFVRQMLEQTKPTTFSELVQISGLSHGTDVWLGNAEELIKNK----TCELPDVIGCRDDIMVFL-------IYQG-------------------LESSLAFKIMESVRKGKGLTDEMEEAMMAN-KVPLWYIESCKKIK-YMFPKAHAAAYVLMAVRIAYFKVHYPLYFYATYFTVRADDFDLTSMVNGKEAVKATMKEVNDKGMEASTKEKNLLTVLEIANEMLARGFHFQKVDLYKSSADEFIIDGESLIPPFNAIPSLGTNVAKQIVAARENGEFLSKEDLQQRGKVSKTIIQYMDDQGCLEGLPDQNQLSLF |
| 2HNH Chain:A ((83-799)) | -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HLTVLAANNTGYQNLTLLISKAYQRGYGAAGPIIDRDWLIELNEGLILLSGGRMGDVGRSLLRGNSALVDECVAFYE--EHFPDRYFL-----ELIRTGRPDEESYLHAAVELAEARGLPVVATNDVRFIDSSDFDAHEIRVAIHDGFTLDDPKRPRNYS--PQQYMRSEEEMCELFADIPEALANTVEIAKRCNVTVRLGEYFLPQFPTGDMSTEDYLVKRAKEGLEERLAFLFPDEEERL--KRRPEYDE-RLETELQVINQMGFPGYFLIVMEFIQWSKDNGVPVGPGRGSGAGSLVAYALKITDLDPL------------EF-----------------------------DLLFERFLNPERVSMPDFDVDFCMEKRDQVIEHVADMYGRDAVSQIITFGTMAAKAVIRDVGRVLGHPYGFVDRISKLIPPDPGMTLAKAFEAEPQLPEIYEADEEVKALIDMARKLEGVTRNAGKHAGGVVIAP--TKITDFAPLY-----CDEEGKHPVTQFDKSDVEYAGLVKFDFLGLRTLTIINWALEMINKRRAKNGEPPLDIAAIPLDDK--------------KSFDMLQRSETTAVFQLESRGMKDLIKRLQPDCFEDMIALVALFRPGPLQSGMVDNFIDRKHGREEISYPDVQWQHESLKPVLEPTYGIILYQEQVMQIAQVLSGYTLGGADMLRRAMGKKKPEEMAKQRSVFAEGAEKNGINAELAMKIFDLVEKFAGYGFNKSHSAAYALVSYQTLWLKAHYPAEFMAAVMTA---DMDNTEKVVG------------------------------------------------------------------------------------------------------------------------------- |
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General information:
TITO was launched using:
| RESULT:
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Template: 2HNH.pdb
Alignment : align.pir
Tito was launched with SMD and SCWRL
Tito text output
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3D Compatibility (PKB) -164991 for 4674 contacts (-35.3/contact) +
2D Compatibility (PS) -66588 + (NN) -27696 + (LL) 57884
1D Compatibility (HY) -32000 + (ID) 9400
Total energy: -242791.0 ( -51.95 by residue)
QMean score : 0.343
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