Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSKVRLYIARHGKTMFNTIGRAQGWSDTPLTTFGELGIKELGLGLKASNISFKEAFSSDSGRTLQTMEIILREVQQENIPYTRDKRIREWCFGSLDGGYDGDLFNGVLPRVSNGDMSHLTHEEIANLICQVDTAGWAEP----------WAILSNRILSGFTAIAKKIEDIGGGNAIVVSHGMTIATFLWL-----IDH--STPRSLGIDNGSVSVVDFEDGTFSIQSIGDMSYREKGREILEKTLQ 1H2E Chain:A ((4-207)) -----LYLTRHGETKWNVERRMQGWQDSPLTEKGRQDAMRLGKRLEA--VELAAIYTSTSGRALETAEIVR---GGRLIPIYQDERLREIHLGDWEGK---------------------THDEIRQMDPIAFDHFWQAPHLYAPQRGERFCDVQQRALEAVQSIVDRHE---GETVLIVTHGVVLKTLMAAFKDTPLDHLWSPPYMYGT---SVTIIEVDGGTFHVAVEGDVSHIEEVKEV------

General information: TITO was launched using: RESULT: Template: 1H2E.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -63819 for 1476 contacts (-43.2/contact) + 2D Compatibility (PS) -19711 + (NN) -7326 + (LL) 1532 1D Compatibility (HY) -10000 + (ID) 3300 Total energy: -102624.0 ( -69.53 by residue) QMean score : 0.421

(partial model without unconserved sides chains): PDB file : Tito_1H2E.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1H2E-query.scw PDB file : Tito_Scwrl_1H2E.pdb: