Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVKVGLVDDYRVDLEKLEAIVSRMQDVEI----VFSTDSAKEAYRRVKNGDIDLLLADIEMPHMSGYELADLIKSHSLDVDVIFVTGHG--GYAVHAFDLNVHDYIMKPYYADRLAASFDRYLKKKTETSLNGRILIKQKSEMHVLQKKDIIFAERTGRSTTIVTTAEEVQTYQTLNDIKGDLPEKDFLRSHRSFIINIHYIKHFSAYTKHSFTVSFEGTSKKAMITKQQLDYFQNYYF 1L5Y Chain:A ((8-122)) -----LIDDDR-DLRK-----AMQQTLELAGFTVSSFASATEALAGLSADFAGIVISDIRMPGMDGLALFRKILALDPDLPMILVTGHGDIPMAVQAIQDGAYDFIAKPFAADRLVQSARRAEKKR-----------------------------------------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 1L5Y.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 510 -65413 -128.26 -600.11 target 2D structure prediction score : 0.68 Monomeric hydrophicity matching model chain A : 0.63 3D Compatibility (PKB) : -128.26 2D Compatibility (Sec. Struct. Predict.) : 0.68 1D Compatibility (Hydrophobicity) : 0.63 QMean score : 0.451

(partial model without unconserved sides chains): PDB file : Tito_1L5Y.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1L5Y-query.scw PDB file : Tito_Scwrl_1L5Y.pdb: