Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDDFKLDKPTPYYLQFYNQLKKMIFNGTFKPGERINETQLAKSFGVSRSPIREAMRLLEKDGLLKADDRNGFSITSLTAKDVDEIYKIRIPLEQLAVELVIDEADEEELTILEKQLEETEKAIHNGTEDTEIIRLNQKFHELLVDFSHNRHLKNLLEH-VNDLIHFCRILNYTGDHRAETILREHRRIFEEVKKKNKEAAKQHVLAHFNHDCEHLKHVLEEGKEN 3C7J Chain:A ((34-233)) ------------------KLRNAIIDGSLPSGTALRQQELATLFGVSRMPVREALRQLEAQSLLRVETHKGAVVAPLITEDAVDAYALRILLESEALRLSIPLLDADDLAAAASYIEQLEVE----TDFGQIGRLNRMFHLSLYAKTHNKRLMRLVEEGLNEEERFLR-FNLSSMGLGKLSQDDHWQLLRLAEQKAVEPCVEALQYHLNRGVQAVTQYLQSQK--

General information: TITO was launched using: RESULT: Template: 3C7J.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 710 -77874 -109.68 -391.33 target 2D structure prediction score : 0.78 Monomeric hydrophicity matching model chain A : 0.75 3D Compatibility (PKB) : -109.68 2D Compatibility (Sec. Struct. Predict.) : 0.78 1D Compatibility (Hydrophobicity) : 0.75 QMean score : 0.618

(partial model without unconserved sides chains): PDB file : Tito_3C7J.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3C7J-query.scw PDB file : Tito_Scwrl_3C7J.pdb: