Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKVFLIGANGQIGQRLVSLFQDNPDHSIRAMVRKEEQKASLEAAGAEAVLANLEGSPEEIAAAAKGCDAIIFTAGSGGSTGYDKTLL-VDLDGAAKAIEAAAIAGIKRFIMVSALQAHNRENW----NEALKPYYVAKHYADKIL-EASGLTYTIIRPGGLRNEPGTGTVSAAKDLERGFISRDDVAKTVIASLDEKNTENRAFDLTEGDTPIAEALKKL 3DQP Chain:A ((2-211)) -KIFIVGSTGRVGKSLLKSLS-TTDYQIYAGARKVEQVP--QYNNVKAVHFDVDWTPEEMAKQLHGMDAIINVSGSGG-----KSLLKVDLYGAVKLMQAAEKAEVKRFILLSTIFSLQPEKWIGAGFDALKDYYIAKHFADLYLTKETNLDYTIIQPGALTEEEATGLIDINDEVSASN-TIGDVADTIKELVMTDHSIGKVISMHNGKTAIKEALESL

General information: TITO was launched using: RESULT: Template: 3DQP.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1135 -121586 -107.12 -596.01 target 2D structure prediction score : 0.55 Monomeric hydrophicity matching model chain A : 0.78 3D Compatibility (PKB) : -107.12 2D Compatibility (Sec. Struct. Predict.) : 0.55 1D Compatibility (Hydrophobicity) : 0.78 QMean score : 0.461

(partial model without unconserved sides chains): PDB file : Tito_3DQP.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3DQP-query.scw PDB file : Tito_Scwrl_3DQP.pdb: