Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLEVKTISVEDTYEIRHRILRPHQSIEQCKYKEDHAEGSFHLGVFYDGTLISIASFSPQSQPLLTEASAYRLRGMATLEGYRDQKAGSTLIKHAEHKLAESGVQAVWCNARHHVKGYYAKLGWKELGEPFDIPGIGNHIVMYKTLRTSR 2JDD Chain:A ((2-145)) -IEVKPINAEDTYELRHRILRPNQPIEACMFESDLLRGAFHLGGYYGGKLISIASFHQAEHSELQGQKQYQLRGMATLEGYREQKAGSSLIKHAEEILRKRGADLLWCNARTSASGYYKKLGFSEQGEVFDTPPVGPHILMYKRI----

General information: TITO was launched using: RESULT: Template: 2JDD.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 703 -78104 -111.10 -542.39 target 2D structure prediction score : 0.74 Monomeric hydrophicity matching model chain A : 0.85 3D Compatibility (PKB) : -111.10 2D Compatibility (Sec. Struct. Predict.) : 0.74 1D Compatibility (Hydrophobicity) : 0.85 QMean score : 0.625

(partial model without unconserved sides chains): PDB file : Tito_2JDD.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2JDD-query.scw PDB file : Tito_Scwrl_2JDD.pdb: