Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MPTEIYVDGASAGNPGPSGIGIFIKHEGKAESFSIPIGVHTNQEAEFLALIEGMKLCATRGYQSVSFRTDSDIVERATELEMVKNITFQPF----------VEEIIRLKAAFPLFFIK--WIPGK----QNQKADLLAKEAIRLNEKN 1GOC Chain:A ((6-140)) ---EIFTDGSCLGNPGPGGYGAILRYRGREKTFSAGYTRTTNNRMELMAAI--VALEALKEHCEVILSTDSQYVRQAITQ-WIHNWKKRGWKTADKKPVKNVDLWQRLDAALGQHQIKWEWVKGHAGHPENERCDELARAA-------

General information: TITO was launched using: RESULT: Template: 1GOC.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 515 -34885 -67.74 -293.15 target 2D structure prediction score : 0.56 Monomeric hydrophicity matching model chain A : 0.79 3D Compatibility (PKB) : -67.74 2D Compatibility (Sec. Struct. Predict.) : 0.56 1D Compatibility (Hydrophobicity) : 0.79 QMean score : 0.443

(partial model without unconserved sides chains): PDB file : Tito_1GOC.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1GOC-query.scw PDB file : Tito_Scwrl_1GOC.pdb: