Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTDQRRNVYFFHKQDQETNEQARSLTQLAEEHGFTVVNQHSDANIIASIGGDGTFLQAVRKTNFR-DDCLYVGITKKGKAHLYCDFHSDEREKMVDAMTFEQIEVRKYPLIEVTVD-QASPFHCLNEVSIRSSIIKTFVMDVLIDDLHFETFRGDGMIISTPTGSTAYNKSVAGAVVDPLLPCMQVSELASLNNNTYRTLGSPFVLSSDRKLTLRVVQDGNEHPIIGLDNEALSTRNVKTIEIKLSNKKIKTVKLKDNSFWEKVKRTFL 2I29 Chain:A ((35-262)) -----------------------------------------EPEIVISIGGDGTFLSAFHQYEERLDEIAFIGI-HT---GFYADWRPAEADKLVKLLAKGEYQKVSYPLLKTTVKY-EATYLALNESTVKSSG-GPFVVDVVINDIHFERFRGDGLCMSTPSGTTAYNKSLGGALMHPSIEAMQLTEMASINNRVYRTIGSPLVFPKHHVVSLQPVNDKDFQ--ISVDHLSILHRDVQEIRYEVSAKKIHFARFRSFPFWRRVHDSFI

General information: TITO was launched using: RESULT: Template: 2I29.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1171 -3460 -2.95 -15.87 target 2D structure prediction score : 0.58 Monomeric hydrophicity matching model chain A : 0.83 3D Compatibility (PKB) : -2.95 2D Compatibility (Sec. Struct. Predict.) : 0.58 1D Compatibility (Hydrophobicity) : 0.83 QMean score : 0.390

(partial model without unconserved sides chains): PDB file : Tito_2I29.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2I29-query.scw PDB file : Tito_Scwrl_2I29.pdb: