Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKKKQVSHAIIISVMLSFVIAVFHTIHASELTPLAQMAEGMERQDVSIDKWTLHAKQNLSLTEKEFYQKVQRLKQEYRQYDWVIAREDKMIKA---IGTYTDKKNRTSFRLQLVTTLKKHNPTSYLLYE------QMSLETPDSWNDTYEQFERETLGIFQEKVVIFTCLNGHLDDNMNIVLQKKANQLLNEFQARSVEHVVEPNFVSISAFTDEWEEYIMTSKHKMNLQIALRSAGMGGKHTVTVGTPIVTTEY 3UV1 Chain:A ((64-141)) ------------------------------------------------------------------------LKQMKRQGDANVKGEEGIVKAHLLIGVHDDI---VSMEYDLAYKLGDLHPTTHVISDIQDFVVALSLEIPDEGNITMTSFE------------------------------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 3UV1.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 179 7383 41.25 107.00 target 2D structure prediction score : 0.39 Monomeric hydrophicity matching model chain A : 0.57 3D Compatibility (PKB) : 41.25 2D Compatibility (Sec. Struct. Predict.) : 0.39 1D Compatibility (Hydrophobicity) : 0.57 QMean score : 0.068

(partial model without unconserved sides chains): PDB file : Tito_3UV1.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3UV1-query.scw PDB file : Tito_Scwrl_3UV1.pdb: