Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKKKSLLPLGLAIGLASLAASPLIQASTYTQTKYPIVLAHGMLGFDNILGVDYWFGIPSALRRDGAQVYVTEVSQLDTSEVRGEQLLQQVEEIVALSGQPKVNLIGHSHGGPTIRYVAAVRPDLIASATSVGAPHKGSDTADFLRQ-IPPGSAGEAVLSGLVNSLGALISFLSSGSTGTQNSLGSLESLNSEGAARFNAKYPQGIPTSACGEGAYKVNGVSYYSWSG------SSPLTNFLDPSDAFLGASSLTFKNGTANDGLVGTCSSHLGMVIRDNYRMNHLDEVNQVFGLTSLFETSPVSVYRQHANRLKNASL 4HS9 Chain:A ((21-307)) -----------------------------MSTKYPIVLVHGLAGFSEIVGFPYFYGIADALTQDGHQVFTASLSAFNSNEVRGKQLWQFVQTILQETQTKKVNFIGHSQGPLACRYVAANYPDSVASVTSINGVNHGSEIADLYRRIIRKDSIPEYIVEKVLNAFGTIISTFSGHRGDPQDAIAALESLTTEQVTEFNNKYPQALPKTPCGEGDEIVNGVHYYCFGSYIQELIAGENGNLLDPTHAAMRVLNTLFTE-KQNDGLVGRCSMRLGKLIKDDYAQDHFDMVNQVAGLVS-YNENIVAIYTLHAKYLASKQL

General information: TITO was launched using: RESULT: Template: 4HS9.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -69029 for 2502 contacts (-27.6/contact) + 2D Compatibility (PS) -30252 + (NN) -11078 + (LL) 2292 1D Compatibility (HY) -25200 + (ID) 6050 Total energy: -139317.0 ( -55.68 by residue) QMean score : 0.500

(partial model without unconserved sides chains): PDB file : Tito_4HS9.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4HS9-query.scw PDB file : Tito_Scwrl_4HS9.pdb: