Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MGKPCHFAQFDLQPAFLVDLDELGQRYRELVRSVHPDRFADAPEREQRLALERAAQLNEAYQTLKSAPRRALYLLTLSGHELPLEATVQDPEFLLQQMQLREELEELQDSADL-AGVATFKRRLKAAQ----AELEREFAAC-WDDAQRREEAERLVRRMQFLDKLAQEVRQLEERLDD 4IT5 Chain:A ((6-172)) -----YFELFGLPIQFELDGSLLSSQFRALQKRFHPDNFATASERDRLMAVQQAAQINDAYQTLKDPLRRAEYLLSLQGIEMN-----QDPMFLMEQMELREELESVTACADPEAALVAFDTKVTAMQRHYLAQLQGQLAQSEWLAAADQ------IRKLKFIAKLKNEVERVEDQL--

General information: TITO was launched using: RESULT: Template: 4IT5.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -42567 for 954 contacts (-44.6/contact) + 2D Compatibility (PS) -17996 + (NN) -20623 + (LL) 1264 1D Compatibility (HY) -14000 + (ID) 3400 Total energy: -97322.0 ( -102.01 by residue) QMean score : 0.719

(partial model without unconserved sides chains): PDB file : Tito_4IT5.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4IT5-query.scw PDB file : Tito_Scwrl_4IT5.pdb: