Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVNLTSMSGFLLMGFSDERKLQILHALVFLVTYLLALTGNLLIITIITVDRRLHSPMYYFLKHLSLLDLCFISVTVPQSIANSLMGNGYISLVQCILQVFFFIALASSEVAILTVMSYDRYAAICQPLHYETIMDPRACRHAVIAVWIAGGLSGLMHA-AINFSIPLCGKRVIHQFFCDVPQMLKLACSYEFINEIALAAFTTSAAFICLISIV-LSYIRIFS--------TVLRIPSAEG-RTKVFSTCLPHLFVATFFLSAAGFEFLRLPSDSSSTVDLVFSVFYTVIPPTLNPVIYSLRNDSMKAALRKMLSKEELPQRKMCLKAMFKL 4DAJ Chain:A ((24-288)) ---------------------------------LVTIIGNILVIVAFKVNKQLKTVNNYFLLSLACADLIIGVISMNLFTTYIIMNRWALGNLACDLWLSIDYVASNASVMNLLVISFDRYFSITRPLTYRA---KRTTKRAGVMIGLAWVISFVLWAPAILFWQYFVGKRT-------VPPG---ECFIQFLSEPTITFGTAIAAFYMPVTIMTILYWRIYKETEKMNIFEMLRID--EGLRLKIYKD------TEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRA

General information: TITO was launched using: RESULT: Template: 4DAJ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -155312 for 1690 contacts (-91.9/contact) + 2D Compatibility (PS) -25805 + (NN) -4555 + (LL) 5144 1D Compatibility (HY) -16800 + (ID) 3450 Total energy: -200778.0 ( -118.80 by residue) QMean score : 0.140

(partial model without unconserved sides chains): PDB file : Tito_4DAJ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4DAJ-query.scw PDB file : Tito_Scwrl_4DAJ.pdb: