Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MESENRTVIREFILLGLTQSQDIQLLVFVLVLIFYFIILPGNFLIIFTIKSDPGLTAPLYFFLGNLAFLDASYSFIVAPRMLVDFLSAKKIISYRGCITQLFFLHFLGGGEGLL-LVVMAFDRYIAICRPLHYPTVMNPRTCYAMMLALWLGGFVHSIIQVVLILRLPF-CGPNQLDNFFCDVPQVIKLAC------------TDTFVVELLMV-FNSGLMTL-LCFLGLLASYAVILCRIRGSSSEAKNKAMSTCITHIIVIFFMF------GPGIFIYTRPFRAF-PADKVVSLFHTVIFPLLNPVIYTLRNQEVKASMKKVFNKHIA 2HPY Chain:A ((56-318)) ---------------------------------------PINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFAT-LGGEIALWSLVVLAIERYVVVCKPMS-----NFRF-----------GENHAIMGVAFTWVMALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIYMFVVHFIIPLIVIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSDFGPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRNCMVTTLCCGKN

General information: TITO was launched using: RESULT: Template: 2HPY.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -206184 for 1790 contacts (-115.2/contact) + 2D Compatibility (PS) -23188 + (NN) 2422 + (LL) 6720 1D Compatibility (HY) -1200 + (ID) 800 Total energy: -222230.0 ( -124.15 by residue) QMean score : 0.098

(partial model without unconserved sides chains): PDB file : Tito_2HPY.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2HPY-query.scw PDB file : Tito_Scwrl_2HPY.pdb: