Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MYVVLEGVDGAGKSTQVGLLKDRFKNA-------LFTKEPGGTRMGESLRRIALNEN-ISELARAFLFLSDRAEHIESVIKPALKEKKLIISDRSLISGMAYSQFSSLELNLLATQSVLPEK------IILLLINKENLKQRLSLKSLDKIENQGIEKLLTIQQKLKTHAYALQEKFGCEVLELDAQKSAKNLHEKIATFIECVV 2WWG Chain:A ((12-194)) -FIVFEGLDRSGKSTQSKLLVEYLKNNNVEVKHLYFPNRETG--IGQIISKYLKMENSMSNETIHLLFSANRWEHMNE-IKSLLLKGIWVVCDRYAYSGVAY---SSGALNLNKTWCMNPDQGLIKPDVVFYLNVPPNYAQNRS----DYGE-EIYEKVETQKKIYETYKHFAHEDYW---INIDATRKIEDIHNDIVKEVTKIK

General information: TITO was launched using: RESULT: Template: 2WWG.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -39419 for 1264 contacts (-31.2/contact) + 2D Compatibility (PS) -17546 + (NN) -490 + (LL) 1436 1D Compatibility (HY) -11200 + (ID) 2750 Total energy: -69969.0 ( -55.36 by residue) QMean score : 0.424

(partial model without unconserved sides chains): PDB file : Tito_2WWG.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2WWG-query.scw PDB file : Tito_Scwrl_2WWG.pdb: