Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MELIIILLALGLLMFTAYRGFSVILFAPICALFAVLLTDPSHVLPFFSSIFMEKMAGFIKLYFPVFLLGAIFGKVVEMAGLAASIAKTIVRLVGAKRAILAIVLMGAVLTYSGVSLFVVVFAVYPFAKNMFQEANIPKRLIPGTIALGAFTFTMDALPGTPQIQNVIPT-------SFFKTDIYAAPWLGLMGAVIVLAAGMLYLESRRKKAQA-----SGEGYGGFDSQNAPAPESIESAAEPDKSPIRHALAFVPLILVGAVNKYFTIYLPKWYPNGFDFSSIGLKEFGRLDISSAAAIWSVEIALVIGIITTILFDWRSVFAQLKEGLNEGIGGALLASMNTG---AEYGFGGIIAALPGFHKL--------SSGISHTFTDPLVNGAVTTTALAGITGSASGGMGIALSAMSEQYLQAIQ--AYNIPPEVMHRVISMASGGMDTLPHNGAVITLLAVTG-----LTHRQSYRDIFAITLIKTAAVFAVIAIYSLTGLV------ 3PJZ Chain:A ((1-484)) MQFRSIIRIVGLLLALFSVTM-------LAPALVALLYRDGAGVPFVTTFFVLLFCGA--------MCWFPNRRHKHELKSRDGFLIVVLFWTVLGSAGSLPFLIADNPNISVTDAFFESFSALTTTG-----ATVIVGLDELPKAILFYRQFLQWFGGMGIIVLAVAILPVLGIGGMTPRIAETAKALWYIYLSLTIACAVAFWLAGMTPFDAISHSFSTIAIGGFSTHDA-------SMGYFDSYAINLITVVFLLISACNFTLHFAAFASG---------GVHPKYYWK---DPEFRAFIFIQVLLFLVCFLLLLK-HHSYTSPYDAFDQALFQTVSISTTAGFTTTGFADWPLFLPVLLLFSSFIGGCAGSTGGGMKVIRILLLTLQGARELKRLVHPRAVYTIKVGGSALPQRVVDAVWGFFSAYALVFVVCMLGLIATGMDELSAFSAVAATLNNLGPGLGEVALHFGDVNDKAKWVLIVSMLFGRLEIFTLLILLTPTFWR

General information: TITO was launched using: RESULT: Template: 3PJZ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2147 -248586 -115.78 -575.43 target 2D structure prediction score : 0.56 Monomeric hydrophicity matching model chain A : 0.65 3D Compatibility (PKB) : -115.78 2D Compatibility (Sec. Struct. Predict.) : 0.56 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.209

(partial model without unconserved sides chains): PDB file : Tito_3PJZ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3PJZ-query.scw PDB file : Tito_Scwrl_3PJZ.pdb: