Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence METVLKAHKVRKVYGSKGNLFSALGSISLEIQKGSFVGIMGPSGAGKSTLLNVLSSIDKPTSGEIEIGGKQISTMNGKELAVFRRDQLGFIFQDYNLLDTMTVKDNIVL-PLALAHIKQAEIDQRFEIIARQFGIFELRNKYPTEISGGQKQRTAVCRAMITEPTLIFADEPTGALDSKSATNLLEGLSQAKDVRDS--TIMMVTHD-AFAASYCERIMFIKDGEIFTE------IYRGTSSR-KQFFQKVLDVLALLGGGENDVI 4U00 Chain:A ((3-242)) --PIIRIRNLHKWFGP----LHVLKGIHLEVAPGEKLVIIGPSGSGKSTLIRTINRLEDFQEGEVVVDG--LSVKDDRALREIRRE-VGMVFQQFNLFPHMTVLENVTLAPMRVRRWPREKAEKKALELLERVGILDQARKYPAQLSGGQQQRVAIARALAMEPKIMLFDEPTSALDPEMVGEVLDVM---RDLAQGGMTMVVVTHEMGFAREVADRVVFMDGGQIVEEGRPEEIFTRPKEERTRSFLQRVL--------------

General information: TITO was launched using: RESULT: Template: 4U00.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -144874 for 1860 contacts (-77.9/contact) + 2D Compatibility (PS) -25000 + (NN) -9889 + (LL) 1456 1D Compatibility (HY) -22400 + (ID) 3850 Total energy: -204557.0 ( -109.98 by residue) QMean score : 0.450

(partial model without unconserved sides chains): PDB file : Tito_4U00.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4U00-query.scw PDB file : Tito_Scwrl_4U00.pdb: