Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MADKNRTFKLVGAGSSSTQEKIEKPALSFMQDAWRRLKKNKLAVVSLYLLALLLTFSLASNLFVTQKDANGFDSKKVTTYRNLPPKLSSNLPFWNGSIKYAGNTESTDAYKSQNVPEKVKYALGTDSLGRSVAKRIIVGIRISLLVAIAATFIDLIIGVTYGLVSGFAGGRLDTLMQRIVEVISSIPNLVIVTMLGLVLGNGITAIIISIAFTGWTSMSRQVRNLTLSYREREFVLAARSLGESPIKIAFKHILPNISGIIIVQIMMTIPSAIMYEAVLSAINLGVKPPTASLGSLISDAQENLQ-YYPYQVILPALALVMISLAFILLGDGLRDAFDPKSSDE 2ONK Chain:C ((24-275)) ----------------------------------MRLLFSALLALLSSIILLFVLLPVAATVTLQLFNFDEFLKAASD-------------PAVWKVVLTTYYAALISTLIAVIFGTPLAYILARKSFPGKSVVEGIVDLPVVIPHTVAGIALLVVFGS-----SGLIG-----------------------SFSPLKFVDALPGIVVAMLFVSVPIYINQAKEGFASV-DVRLEHVARTLGSSPLRVFFTVSLPLSVRHIVAGAIMSWARGISEFGAVVVI--AYYPMIAPTLIYERYLSEGLSAAMPVAAILILLSLAVFVALRIIVG--------------

General information: TITO was launched using: RESULT: Template: 2ONK.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -113843 for 1861 contacts (-61.2/contact) + 2D Compatibility (PS) -26117 + (NN) -1366 + (LL) 5436 1D Compatibility (HY) -14800 + (ID) 2300 Total energy: -152990.0 ( -82.21 by residue) QMean score : 0.180

(partial model without unconserved sides chains): PDB file : Tito_2ONK.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2ONK-query.scw PDB file : Tito_Scwrl_2ONK.pdb: