Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKNDQIVFEKTKNIAHDINQMQNQQEIIDYLFRQDSLTLNQLKHYYSEPSLPLQFLVKVAVLCMFISMTLASFL-FIQAKEVFTNTILSDISPAVFSIFTVICIFMTYTKIIKKGNKNKGKASLNQRSEFY---EKNKLINTILYKKYKMDQQNIQANKHTASDN-----EDSMNFSAVLNHVLTISKNDKELLGYLDTRDNAMLSQLKAYFSTRPFS--------------LPHYMSLMFCGSIIVVYATSL--FSGQINYIDIPHIFIFLLLIIFLKILIDLIKLLNI-SRKGQLHTVLHFAQRAEYLRMRGV-IDFILTERYNKKIM 3GOD Chain:A ((7-326)) ------DISPSELKTILHSKRANLYYLQHCRVLVNGGRVEYVTDEGRHSHYWNIPIANTTSLLLGTGTSITQAAMRELARA---GVLVGFCGGGGTPLFSANEVDVEVSWLTPQSEYRPTEYLQRWVGFWFDEEKRLVAARHFQRARLERIRHSWLEDRVLRDAGFAVDATALAVAVEDSARALEQAPNHEHLLTEEARLSKRLFKLAAQATRYGEFVRAKRGSGGDPANRFLDHGNYLAYGLAATATWVLGIPHGLAVLHGKTRRGGLVFDVADLIKDSLILPQAFLSAMRGDEEQDFRQACLDNLSRAQALDFMI-DTLKDVAQRSTV

General information: TITO was launched using: RESULT: Template: 3GOD.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1391 -166585 -119.76 -568.55 target 2D structure prediction score : 0.49 Monomeric hydrophicity matching model chain A : 0.59 3D Compatibility (PKB) : -119.76 2D Compatibility (Sec. Struct. Predict.) : 0.49 1D Compatibility (Hydrophobicity) : 0.59 QMean score : 0.195

(partial model without unconserved sides chains): PDB file : Tito_3GOD.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3GOD-query.scw PDB file : Tito_Scwrl_3GOD.pdb: