Modeling by threading (Tito software)
Unconserved sides chains calculation (Scwrl software)
Evaluation (QMean software)



Input alignment information:
Query sequence-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEKLFKEVKLEELENQKGSGLGKAQCAALWL--QCASGGTIGCGGGAVACQNYRQFCR--------------------------------
4C4A Chain:A ((27-688))HQEIARSSYADMLHDKDRNIKYYQGIRAAVSRVKDRGQKALVLDIGTGTGLLSMMAVTAGADFCYAIEVFKPMAEAAVKIVERNGFSDKIKVINKHSTEVTVGPDGDLPCRANILITELFDTELIGEGALPSYEHAHKHLVQEDCEAVPHRATVYAQLVESRRMWSWNKLFPVRVRTSLGEQVIVPPSELERCPGAPSVCDIQLNQVSPADFTVLSDVLPMFSVDFSKQVSSSAACHSRQFVPLASGQAQVVLSWWDIEMDPEGKIKCTMAPFWAQTDPQELQWRDHWMQCVYFLPQEEPVVQGSPRCLVAHHDDYCVWYSLQRTSPQVRPVCDCQAHLLWNRPRFGEINDQDRTDHYAQALRTVLLPGSVCLCVSDGSLLSMLAHHLGAEQVFTVESSVASYRLMKRIFKVNHLEDKISVINKRPELLTAADLEGKKVSLLLGEPFFTTSLLPWHNLYFWYVRTSVDQHLAPGAVVMPQAASLHAVIVEFRDLWRIRSPCGDCEGFDVHIMDDMIKHSLDFRESREAEPHPLWEYPCRSLSKPQEILTFDFQQPIPQQPMQSKGTMELTRPGKSHGAVLWMEYQLTPDSTISTGLINPGDCCWNPHCKQAVYFLSTPRSVSYVVEFHPLTGDITMEFRLA


General information:
TITO was launched using:
RESULT:

Template: 4C4A.pdb
Alignment : align.pir
Tito was launched with SMD and SCWRL
Tito text output
Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 86 3564 41.44 63.64
target 2D structure prediction score : 0.27
Monomeric hydrophicity matching model chain A : 0.51

3D Compatibility (PKB) : 41.44
2D Compatibility (Sec. Struct. Predict.) : 0.27
1D Compatibility (Hydrophobicity) : 0.51
QMean score : 0.124

(partial model without unconserved sides chains):
PDB file : Tito_4C4A.pdb:





(Unconserved sides chains are recalculated) :
Sequence: align-4C4A-query.scw
PDB file : Tito_Scwrl_4C4A.pdb: