Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLEQPIGVIDSGVGGLTVAKEIMRQLPKENIIYVGDTKRCPYGPRPEEEVLQYTWELTNYLLENHHIKMLVIACNTATAIALDDIQRSVGIPVVGVIQPGARAAIKV--TDNQHIGVIGTENTIKSNAYEEALLALNPDLKVENLACPLLVPFVESGKFLDKTADEIVKTSLYPLKD-TSIDSLILGCTHYPILKEAIQRYMGEHVNIISSGDETAREVSTILSYKGLLNQSPIAPDHQFLTTGARDQFAKIADDWFGHEVGHVECISLQEPIKR 3UHF Chain:A ((26-229)) ----KIGVFDSGVGGLSVLKSLYEARLFDEIIYYGDTARVPYGVKDKDTIIKFCLEALDF-FEQFQIDMLIIACNTASAYALDALRAKAHFPVYGVIDAGVEATIKALHDKNKEILVIATKATIKSEEYQKRLLS-QGYTNINALATGLFVPMVEEGIF---EGDFLQSAMEYYFKNITTPDALILACTHFPLLGRSLSKYFGDKTKLIHSGD--------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 3UHF.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1081 -87279 -80.74 -434.22 target 2D structure prediction score : 0.65 Monomeric hydrophicity matching model chain A : 0.78 3D Compatibility (PKB) : -80.74 2D Compatibility (Sec. Struct. Predict.) : 0.65 1D Compatibility (Hydrophobicity) : 0.78 QMean score : 0.513

(partial model without unconserved sides chains): PDB file : Tito_3UHF.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3UHF-query.scw PDB file : Tito_Scwrl_3UHF.pdb: