Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEAVSPIRRFTVDGVNVYYEHYQNPGR-QTLVCVHGFLSSAFS----FRKVIPLLRDKYDIIALDLPPFGQSE-----KSRTFIYTYQNLAKLVIGILEHLQVKQAVLVGHSMGGQISLSAALQKPELFSKVVLLCSSGYLKRSH-PTIIFGTHIPYFHLYIKRWLSKEGVMKNLLNVVHDKSLIDEEMIDGYGRPFQDEQIFKAMTRFIRHREGDLE----PEQLKKMNKPALLIWGEEDRIVPMEIGKRLHADLPNSVLYSLGQTGHLVPEERPELISEHIADFIK 2OG1 Chain:A ((8-284)) --STSKFVKINEKGFSDFNIHYNEAGNGETVIMLHGGGPGAGGWSNYYRNVGPFVDAGYRVILKDSPGFNKSDAVVMDEQRGLVN-----ARAVKGLMDALDIDRAHLVGNSMGGATALNFALEYPDRIGKLILMGPGGLGPSMFAPMPMEGIKL-LFKLYAEP--SYETLKQMLQVFLYDQSLITEELLQGRWEAIQ-RQPEHLKNFLISAQKAPLSTWDVTARLGEIKAKTFITWGRDDRFVPLDHGLKLLWNIDDARLHVFSKCGHWAQWEHADEFNRLVIDFLR

General information: TITO was launched using: RESULT: Template: 2OG1.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1586 -26268 -16.56 -100.26 target 2D structure prediction score : 0.56 Monomeric hydrophicity matching model chain A : 0.75 3D Compatibility (PKB) : -16.56 2D Compatibility (Sec. Struct. Predict.) : 0.56 1D Compatibility (Hydrophobicity) : 0.75 QMean score : 0.412

(partial model without unconserved sides chains): PDB file : Tito_2OG1.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2OG1-query.scw PDB file : Tito_Scwrl_2OG1.pdb: