Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MYIIMGVFTTIVNIASFYILVEIMNVDYKAATVAAWILSVLFAY-----ITNKLYVFQQKTHDLQSLLKELTAFFSVRVLSLGIDLGMMIILVGQFNTNETLAKILDNAVIVVVNYVASKWLVFKKTKEEGV----------- 3UUN Chain:A ((338-453)) -------------------EVNLDRYQTALEEVLSWLLSAEDTLQAQGEISNDVEVVKDQFHTHEGYMMDLTAHQG-RVGNI-LQLGSKLIGTGKLS------EDEETEVQEQMNLLNSRWECLRVASMEKQSNLHRVLMDLQ

General information: TITO was launched using: RESULT: Template: 3UUN.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 213 1330 6.24 13.30 target 2D structure prediction score : 0.49 Monomeric hydrophicity matching model chain A : 0.61 3D Compatibility (PKB) : 6.24 2D Compatibility (Sec. Struct. Predict.) : 0.49 1D Compatibility (Hydrophobicity) : 0.61 QMean score : 0.338

(partial model without unconserved sides chains): PDB file : Tito_3UUN.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3UUN-query.scw PDB file : Tito_Scwrl_3UUN.pdb: