Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEQQLKDIISACDLAIQNEDFDTLMNYYSEDAVLVVKPGM-IARGKEEIKKAFITIANYFNHHIVPTQGKMILLEAGDTVLVLSQTLLDSDKKDSEYAMERRATYVFKKNAQ---GEWLCVIDNSYGTDLIGV 5IG0 Chain:A ((18-143)) -AKAVLEVNDELLKAVASGDWDAYTTMVDPNVTCFEPEAAGVLAKGLAFHKFFFDNRSPNADKMKTTLHDPAVQMFGDTAIVTALRVVQFVADDGPKTTRYEETRVWVKD-AAFKFGWKLVHFHRSGA-----

General information: TITO was launched using: RESULT: Template: 5IG0.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 462 -22041 -47.71 -180.66 target 2D structure prediction score : 0.61 Monomeric hydrophicity matching model chain A : 0.61 3D Compatibility (PKB) : -47.71 2D Compatibility (Sec. Struct. Predict.) : 0.61 1D Compatibility (Hydrophobicity) : 0.61 QMean score : 0.369

(partial model without unconserved sides chains): PDB file : Tito_5IG0.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5IG0-query.scw PDB file : Tito_Scwrl_5IG0.pdb: