Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MADAPTRATTSRVDSDLDAQSPAADLVRVYLNGIGKTALLNAAGEVELAKRIEAGLYAEHLLETRKRLGENRKRDLAAVVRDGEAARRHLLEANLRLVVSLAKRYTGRGMPLLDLIQEGNLGLIRAMEKFDYTKGFKFSTYATWWIRQAITRGMADQSRTIRLPVHLVEQVNKLARIKREMHQHLGREATDEELAAESGIPID--KINDLLEHSRDPVSLDMPVGSEEEAPLGDFIEDAEAMSAENAVIAELLHTDIRSVLATLDEREHQVIRLRFGLDDGQPRTLDQIGKLFGLSRERVRQIERDVMSKLR-HGERADRLRSYAS 4Q5S Chain:F ((164-421)) -----------------------------------------------------------------KSLPKEHKRYLH-IAREGEAARQHLIEANLRLVVSIAKKYTGRGLSFLDLIQEGNQGLIRAVEKFEYKRRFKFSTYATWWIRQAINRAIADQARTIRIPVHMVETINKLSRTARQLQQELGREPTYEEIAEAMGPGWDAKRVEETLKIAQEPVSLETP-------FYGDFIPDEHLPSPVDAATQSLLSEELEKALSKLSEREAMVLKLRKGLIDGREHTLEEVGAFFGVTRERIRQIENKALRKLKYHESRTRKLRDF--

General information: TITO was launched using: RESULT: Template: 4Q5S.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -68540 for 1467 contacts (-46.7/contact) + 2D Compatibility (PS) -27204 + (NN) -15530 + (LL) 5568 1D Compatibility (HY) -22000 + (ID) 6750 Total energy: -134456.0 ( -91.65 by residue) QMean score : 0.593

(partial model without unconserved sides chains): PDB file : Tito_4Q5S.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4Q5S-query.scw PDB file : Tito_Scwrl_4Q5S.pdb: