Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence ----------------------------MATYNAIIYSGGYSQTLRDFAGWTGDLLTTI-QDMKLHAQEFNSPYDAAMKIIGNMYQ--------------------FSLDDLFSDVDAINLA----NKTSVGANAQPLNIAIRDYYSNNDCMNRF-------TQFV-NNRFDGSLDKIFSEAEYYLNTNLDP---VVVPIRLAFKRAFDVEDYSEEIGKITAQAFRDVIEKKMISE 3P42 Chain:A ((3-236)) QGMVTIYLPGEQQTLSVGPVENVAQLVTQPQLRDRLWWPGALLTDSAAKAKALKDYQHVMAQLASWEAEADDDVAATIKSVRQQLLNLNITGRLPVKLDPDFVRVDENSNPPLVGDYTLYTVQRPVTITLLGAVSGAGQLPWLAGRSVTDYLQDHPRLAGADKNNVMVITPEGETVVAPVALWNKRHVEPPPGSQLWLGFSAH-VLPEKYADLNDQIVSVLTQRVPELEHHHHHH-

General information: TITO was launched using: RESULT: Template: 3P42.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 587 -60855 -103.67 -357.97 target 2D structure prediction score : 0.45 Monomeric hydrophicity matching model chain A : 0.58 3D Compatibility (PKB) : -103.67 2D Compatibility (Sec. Struct. Predict.) : 0.45 1D Compatibility (Hydrophobicity) : 0.58 QMean score : 0.144

(partial model without unconserved sides chains): PDB file : Tito_3P42.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3P42-query.scw PDB file : Tito_Scwrl_3P42.pdb: