Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKRRTAREKALQALFQIDVSDIAVNEAIEH--ALDEEKTD-----PFFEQLVHGVLEHQDQLDEMISKHLVNWKLDRIANVDRAILRLAAYEMAYAEDIPVNVSMNEAIELAKRFGDDKATKFVNGVLSNIKSDIEQS 1EYV Chain:B ((10-138)) --RHQARKRAVALLFEAEVRGISAAEVVDTRAALAEAKPDIARLHPYTAAVARGVSEHAAHIDDLITAHLRGWTLDRLPAVDRAILRVSVWELLHAADVPEPVVVDEAVQLAKELSTDDSPGFVNGVLGQV-------

General information: TITO was launched using: RESULT: Template: 1EYV.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 492 -18372 -37.34 -150.59 target 2D structure prediction score : 0.72 Monomeric hydrophicity matching model chain B : 0.83 3D Compatibility (PKB) : -37.34 2D Compatibility (Sec. Struct. Predict.) : 0.72 1D Compatibility (Hydrophobicity) : 0.83 QMean score : 0.644

(partial model without unconserved sides chains): PDB file : Tito_1EYV.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1EYV-query.scw PDB file : Tito_Scwrl_1EYV.pdb: