Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MERKTVLYIAVSLDGMIAKEDGSIDWLD--EFEGEGDNGYSDFYQTVDTVILGRSTYEHVKVLTPVFPYQDKTCYVFTGSPDSYQDEHV--TFINEGARAFTARLKQEKGSNIWIAGGAELVNDFMKEDAIDEFIITVIPVVLGSG---IPLFHELTNETKLRLKGTKQFGQAVQLHYVRA 2XW7 Chain:B ((5-162)) ---KTVYYTASSLDGYIVDENQSLDWLTSRDITPDGPFGYEQFIETIGVLVMGASTYEWV-VEHGDWSY-DQPAWVLTHRPEIAAESHPMQVFSGDVAELHPELVAAAGGKDVWVVGGGDVAAQFVAADLIDEIIVSYAPCTLGVGSRVLPMRSEWVLDDCAR------------------

General information: TITO was launched using: RESULT: Template: 2XW7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 675 -37343 -55.32 -247.30 target 2D structure prediction score : 0.54 Monomeric hydrophicity matching model chain B : 0.76 3D Compatibility (PKB) : -55.32 2D Compatibility (Sec. Struct. Predict.) : 0.54 1D Compatibility (Hydrophobicity) : 0.76 QMean score : 0.529

(partial model without unconserved sides chains): PDB file : Tito_2XW7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2XW7-query.scw PDB file : Tito_Scwrl_2XW7.pdb: