Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKEARKRMVKRAVQEIKDGMNVNLGIGMPTLVANEIPDGVHVMLQSENGLLGIGPYPLEGTEDADLINAGKETITEVTGASYFDSAESFAMIRGGHIDLAILGGMEVSEQGDLANWMIPGKMVKGMGGAMDLVNGAK-RIVVIMEHVNKHGESKVKKTCSLPLTGQKVVHRLITDLAVFDFVNGR-MTLTELQDGVTIEEVYEKTEADFAVSQSVLNS 3DLX Chain:C ((262-475)) --DVRERIIKRAALEFEDGMYANLGIGIPLLASNFISPNITVHLQSENGVLGLGPYPRQHEADADLINAGKETVTILPGASFFSSDESFAMIRGGHVDLTMLGAMQVSKYGDLANWMIPGKMVKGMGGAMDLVSSAKTKVVVTMEHSAKGNAHKIMEKCTLPLTGKQCVNRIITEKAVFDVDKKKGLTLIELWEGLTVDDVQKSTGCDFAVSPKLM--

General information: TITO was launched using: RESULT: Template: 3DLX.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 1101 -57210 -51.96 -269.86 target 2D structure prediction score : 0.48 Monomeric hydrophicity matching model chain C : 0.87 3D Compatibility (PKB) : -51.96 2D Compatibility (Sec. Struct. Predict.) : 0.48 1D Compatibility (Hydrophobicity) : 0.87 QMean score : 0.537

(partial model without unconserved sides chains): PDB file : Tito_3DLX.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3DLX-query.scw PDB file : Tito_Scwrl_3DLX.pdb: