Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence ---MELIIILLALGLLMFTAYRGFSVILFAPICALFAVLLTDPSHVLPFFSSIFMEKMAGFIKLYFPVFLLGAIFGKVVEMAGLAASIAKTIVRLVGAKRAILAIVLMGA-------VLTYSGVSLFVVVFAVYPFAKNMFQEANIPKRLIPGTIALGAFTFTMDALPGTPQIQNVIPTSFFKTDIYAAPWLGLMGAVIVLAAGMLYLESRRKKAQASGEGYGGFDSQNAPAPESIESAAEPDKSPIRHALAFVPLILVGAVNKYFTIYLPKWYPNGFDFSSIGLKEF-GRLDISSAAAIWSVEIALVIGIITTILFDWRSVFAQLKEGLN----EGIGGALLASMN--TGAEYGFGGIIAALPGFHKLSSGISHTFTDPLVNGAVTTTALAGITGSASGGMGIALSAMSEQYLQAIQAYNIPPEVMHRVISMASGGMDTLPHNGAVITLLAVTGLTHRQSYRDIFAITLIKTAAVFAVIAIYSLTGLV-- 3JA7 Chain:A ((70-516)) NWISELIDTYRNL-------MNNYEVDNAVSEIVSDAIVYEDDTEVVAL--NLDKSKFSPKIKN-----MMLDEFSDVLNHLSFQRKGSDHFRRWYVDSRIFFHKIIDPKRPKEGIKELRRLDPRQVQYVYFIYDTAHESY--------------ACDGRMYEAGTKIKIPK-AAVVYAHSGLVDCCGKNIIGYLHRAVKPANQLKLLEDAVVIYRITR------------APDRRVWYVDTGNMPARKAAEHMQHVMNTMKNRVVYDASTGKIKNQQHNMSMTEDYWLQRRDGKAVTEVDTLPGADNTGNMEDIRWFRQALYMALRVPLSRIPQDQQGGVMFDSGTSITRDELTFAKFIRELQ--HKFE----EVFLDPLKTNLLLKGIITEDEWNDEIN-NIKIEFHRDSYFAELK----EAEILERRINMLTMAE---PFIGKYIS--------HRTAMKDILQMTDEEIEQEAKQIEEESKEARFQD

General information: TITO was launched using: RESULT: Template: 3JA7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1294 -63111 -48.77 -154.31 target 2D structure prediction score : 0.45 Monomeric hydrophicity matching model chain A : 0.62 3D Compatibility (PKB) : -48.77 2D Compatibility (Sec. Struct. Predict.) : 0.45 1D Compatibility (Hydrophobicity) : 0.62 QMean score : 0.039

(partial model without unconserved sides chains): PDB file : Tito_3JA7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3JA7-query.scw PDB file : Tito_Scwrl_3JA7.pdb: