Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKTSNTKTPKPVLIAGPCVIESLENLRSIAIKLQPLANN-ERLDFYFKASFDKANRTSLESYRGPGLEKGLEMLQTIKDEFGYKILTDVHESYQASVAAKVADILQIPAFLCRQTDLIVEVSQTNAIVNIKKGQFMNPKDMQYSVLKALKTRDSSIQSPTYETALKNGVWLCERGSSFGYGNLVVDMRSLKIMREFAPVIFDATHSVQMPGGANGKSSGDSSFPPILPRAAAAVGIDGLFAETHIDPKNALSDGANMLKPDELEHLVTDMLKIQNLF 3E12 Chain:B ((3-256)) ---------KFLVIAGPCAIESEELLLKVGEEIKRLSEKFKEVEFVFKSSFDKANRSSIHSFRGHGLEYGVKALRKVKEEFGLKITTDIHESWQAEPVAEVADIIQIPAFLCRQTDLLLAAAKTGRAVNVKKGQFLAPWDTK-NVVEKLKFGGA------------KEIYLTERGTTFGYNNLVVDFRSLPIMKQWAKVIYDATHSVQLPG------GGMREFIFPLIRAAVAVGCDGVFMETHPEPEKALSDASTQLPLSQLEGIIEAILEIREVA

General information: TITO was launched using: RESULT: Template: 3E12.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -134526 for 2152 contacts (-62.5/contact) + 2D Compatibility (PS) -27004 + (NN) -12065 + (LL) 904 1D Compatibility (HY) -24800 + (ID) 6400 Total energy: -203891.0 ( -94.74 by residue) QMean score : 0.589

(partial model without unconserved sides chains): PDB file : Tito_3E12.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3E12-query.scw PDB file : Tito_Scwrl_3E12.pdb: