Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MILSIESSCDDSSLALTRIEDAKLIAHFKISQEKHHSSYGGVVPEIASRLHA-ENLPLLLERVKIS--LNKDFSKIKAIAITNQPGLSVTLIEGLMMAKALSLSLNLPLILEDHLRGHVYSLFINEKQTRMPLSVLLVSGGHSLILEARDYEDIKIVATSLDDSFGESFDKVSKMLDLGYPGGPIVEKLALDYAHPNEPLMFPIPLKNSPNLAFSFSGLKNAVRLEVEKNAHNLNDEVKQKIGYHFQSAAIEHLIQQTKRYFKIKRPKIFGIVGGASQNLALRKAFEDLCAEFDCELVLAPLEFCSDNAAMIGRSSLEAYQKKRFIPLEKADISPRTLLKNFE 4WQ4 Chain:B ((3-314)) -VLGIETSCDATGIAIYDDEKG-LLANQLYSQVKLHADYGGVVPELASRDHVRKTVPLIQAALKESGLTAKD---IDAVAYTAGPGLVGALLVGATVGRSLAFAWDVPAIPVHHMEGHLLAPMLEDNPPEFPFVALLVSGGHTQLISVTGIGQYELLGESIDDAAGEAFDKTAKLLGLDYPGGPLLSKMAAQGTAGR--FVFPRPMTDRPGLDFSFSGLKTFAANTIRDN--GTDDQTRADIARAFEDAVVDTLMIKCKRALDQTGFKRLVMAGGVSANRTLRAKLAEMMKKRRGEVFYARPEFCTDNGAMIAYAGMVRFKAGATADLGVSVRPRWPLAELPA

General information: TITO was launched using: RESULT: Template: 4WQ4.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -186098 for 2782 contacts (-66.9/contact) + 2D Compatibility (PS) -33545 + (NN) -16234 + (LL) 592 1D Compatibility (HY) -20800 + (ID) 5450 Total energy: -261535.0 ( -94.01 by residue) QMean score : 0.458

(partial model without unconserved sides chains): PDB file : Tito_4WQ4.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4WQ4-query.scw PDB file : Tito_Scwrl_4WQ4.pdb: