Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKSFQALFIEKEADNTSLHFRETTIDN-LPENEVTIEVHYSGINYKDGLAVLPDGKIVSEYPFIPGIDASGVVVNSKSDQFQVGDEVIVTSYDFGVSYFGGYSEFIRVPAEWVVPLPDGLSLKEAMILGTAGFTAALSVDALEFSGVTPNAGKIAVSGATGGVGSLSSAILSKRGFSVVASSGKSDAKEFLEKFGVSEIVSREAFQPEKVRALDKQLYAGAIDCVGGKPLSYLLTAVQYGGAVTTCGMSAGGKLDTTVFPFILRGIQLFGIDSVLCPMSKRERIWNRLATDYKLTNLESLATEIAFSELPESLHQVMNGGVTGRYLVKVK 4JXK Chain:B ((25-349)) --EFTA-WIARENEGAIGLSQETVGESFLPQGEVTIQVEYSSVNFKDALALTPKGGVVREYPIVPGIDVAGTVVESQSPEFSVGDTVVAHGYDIGTARHGGYAQFARVPADWVVKL-DGMSTRTAAAIGTAGFTAAMSVEALQSRGVEPGNGPVLVTGASGGVGTVAVDLLSAAGFEVVASSGKPEKAELLTQLGASKVIGRLPEPDTKPRPLGKAQWAAAVDCVGGATLAHVLSTIEYGGAVAASGLTGGPKLETTVLPFILRGVSLLGIDSVQYPIDQRRRLWGRLASDLAPSRLESITHDVPIADVVSVIDQVRAGTYSGRAVVAV-

General information: TITO was launched using: RESULT: Template: 4JXK.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -207438 for 2930 contacts (-70.8/contact) + 2D Compatibility (PS) -34827 + (NN) -9352 + (LL) 372 1D Compatibility (HY) -28000 + (ID) 7650 Total energy: -286895.0 ( -97.92 by residue) QMean score : 0.623

(partial model without unconserved sides chains): PDB file : Tito_4JXK.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4JXK-query.scw PDB file : Tito_Scwrl_4JXK.pdb: