Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTYIVQTNGLTKTYQGKEVVS--NVSMHIKKGEIYGFLGPNGAGKTTIMKMLTSLVKPTSGEIIILGNKFTHTSYEVL-----GNIGSMIEYPIFYENLTAEENLDLHCEYMGYHN---KKAIQEVLDMVNLKQIDKKPVKTFSLGMKQRLGIARAILTKPDLLILDEPVNGLDPLGIKKIRQLFQVLSKEYGMTLLISSHLLGEIEQIADTIGVIRDGRLLEEVSMEDVRGQNTEYIELVTPNQTRACFVLEKELQLTNFKILNEKTIRIYEAEASQAAISKALILNDVDIESMNKKYTSLEDYFIKLINGNSISA 1OXV Chain:D ((1-228)) MVRIIVKN-VSKVFKKGKVVALDNVNINIENGERFGILGPSGAGKTTFMRIIAGLDVPSTGELY-FDDRLVASNGKLIVPPEDRKIGMVFQTWALYPNLTAFENIAFPLTNMKMSKEEIRKRVEEVAKILDIHHVLNHFPRELSGGQQQRVALARALVKDPSLLLLDEPFSNLDARMRDSARALVKEVQSRLGVTLLVVSHDPADIFAIADRVGVLVKGKLVQVGKPEDL---------------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 1OXV.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain D - contact count / total energy / energy per contact / energy per residue : 1130 -143865 -127.31 -659.93 target 2D structure prediction score : 0.58 Monomeric hydrophicity matching model chain D : 0.73 3D Compatibility (PKB) : -127.31 2D Compatibility (Sec. Struct. Predict.) : 0.58 1D Compatibility (Hydrophobicity) : 0.73 QMean score : 0.523

(partial model without unconserved sides chains): PDB file : Tito_1OXV.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1OXV-query.scw PDB file : Tito_Scwrl_1OXV.pdb: