Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence M--WEQLYDPFGNEYVSALVALTPILFFLL-ALTVLKMKGILAAFLTLAVSFFVSVWAFHMPVEKAISSVLLGIGSGLWPIGYIVLMAVWLYKIAVKTGKFTIIRSSIAGISPDQRLQLLLIGFCFN--AFLEGAAGFGVPIAISAALLVELGFKPLKAAALCLIANAASGAFGAIGIPVITGAQIGDLSALELSRTLMWTLPMISFLIPFLLVFLLDRMKGIKQTWPALLVVSGGYTAVQTLTMAVLGPELANILAALFSMGGLALFLRKWQP---KEIYRE--EGAGDAGEKKAYRAADIAKAWSPFYILTAAITIWSLPAFKALFQEGGLLYQSTLLFKMP--FLHQQIMKM-PPIAPSAMPLDAVFKVDLLSATGTAILAAVIVTGLFSKKFSSRDAFASLKETGKELWVPIMTICFVMGFANLANFAGLSSSIGLALAKTGDLFPFVSPVLGWIGVFITGSVVSNNALFGHLQVVTGAQIGAGSDLLLAANTAGGVMAKLVSPQSIAIAAAAVGQTGKESKLFKRTVAYSLILLLIICIWTFILARLGV 4YB8 Chain:A ((1-464)) MNDLERLFNPSAIAVVGASKDPSKIGSQILRNLLSYGFKGKVYPINPTADELM------GLKCYPKVSDVPDKVDVAVISVPSDKVLGV-IDDCGKAGVKFAVVITSGFKEVGNEELEEELVRRAHSYGMRVLGPNIFGYLYAPAR-LNATFGPKDVLSGNVAFISQSGALGIALMGYTVVENIGISSIVSVGNKADLD--------DVDLLDFFDKDPNTGVIMIYLEGIAPGRGRMFIDVASRVSLRKPIIVIKAGRTEVGARAAASHTGSIAGSVAIYESAFKQSGILMAKSVEDAFDWTKALSWNPIPEGERLIVLTNGGGAGVQSTDTFADNGIYLSKPPESLIQEIKKFVPPFASFANPID--------------------ITGMAPDDWYYMGTLAALKNPD----VDALTVLYCQT--AVTTPIGVAKGIVDAIKEAGNSKPVTVGMVG------------------------GPEVAEAVSFLNKQRI-----AAYPTPERASSAMSALYAYARARSYVMKSLAVR-------------------

General information: TITO was launched using: RESULT: Template: 4YB8.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2730 -338136 -123.86 -749.75 target 2D structure prediction score : 0.36 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : -123.86 2D Compatibility (Sec. Struct. Predict.) : 0.36 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.209

(partial model without unconserved sides chains): PDB file : Tito_4YB8.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4YB8-query.scw PDB file : Tito_Scwrl_4YB8.pdb: