Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDFEKIRKWLEITNEYKQSDFWTNV-LKYKAPEHFFDSEASTFVYDFYQDEEYNFIIVEMPGVYEEELTIRLLSKTQLLIKGTITPVF----PAEMEVLRERYYGEIERIIQLPEAAETHLLQIQLLNGLLHISYPRQVETVAFNKGL 3W1Z Chain:A ((10-136)) ---------PPTVNDLFSDFVSYSPRLNN------QIPGELSPSIDVHEGKDTVSVDVELPGVKKEDVQVHYDS-GKLTISGEVVNERKNESTEGNQRWSERRFGSFSRTITIPAKIDADRIEANFSNGLLTVTLPKVEKSQT-----

General information: TITO was launched using: RESULT: Template: 3W1Z.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 451 -52092 -115.50 -426.98 target 2D structure prediction score : 0.48 Monomeric hydrophicity matching model chain A : 0.69 3D Compatibility (PKB) : -115.50 2D Compatibility (Sec. Struct. Predict.) : 0.48 1D Compatibility (Hydrophobicity) : 0.69 QMean score : 0.251

(partial model without unconserved sides chains): PDB file : Tito_3W1Z.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3W1Z-query.scw PDB file : Tito_Scwrl_3W1Z.pdb: