Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKVVSLFSGIGGIELGLHQSGHTTEIFCEVDPLAKAVLSKNFPGVKIEDDINEIR--ELPSCDLVAAGFPCQDLSQAGGKEGIDGSRSGLVKKLFELIEKKEHANRPPWILIENVPYMLRLNRGKAMSYLTSVLSELGYTWAYRTVDARCFGLPQRRHRVILLASLFE-DPKDVIFSQDHSEP-DLDGKPSVVDHS----NYY------GFYWT----------------EGLRGVGWAREAVPPIKCGSSVGIASPPAVWSPYEDIVGTINIRDAERLQGFPEDWTNITTETGKDIKEGARWRLVGNAVSVRVSKWIGENLSQPKGSISDFEGELVTKTWPSAAWGYGDKKYKVPVSKWVANTEQIAISEFLNHPLKPLSARALNGFLGRAARCTNVNYSDEFINSLERCKDRQLQKV 5CIY Chain:A ((12-324)) LRFIDLFAGLGGFRLALESCGAECVYSNEWDKYAQEVYEMNFGEK-PEGDITQVNEKTIPDHDILCAGFPCQAFSISGKQKGFEDSRGTLFFDIARIVREK----KPKVVFMENVKNFASHDNGNTLEVVKNTMNELDYSFHAKVLNALDYGIPQKRERIYMICFRNDLNIQNFQFPKPFELNTFVKDLLLPDSEVEHLVIDRKDLVMTNQEIEQTTPKTVRLGIVGKGGQGERIYSTRGI-AITLSAYGGGIFAKTG--GYLVNGKTRKLHPRECARVMGYPDSYK-------VHPSTSQAYKQFGNSVVINVLQYIAYNIGSSLNF-------------------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 5CIY.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1607 -143557 -89.33 -507.27 target 2D structure prediction score : 0.61 Monomeric hydrophicity matching model chain A : 0.68 3D Compatibility (PKB) : -89.33 2D Compatibility (Sec. Struct. Predict.) : 0.61 1D Compatibility (Hydrophobicity) : 0.68 QMean score : 0.449

(partial model without unconserved sides chains): PDB file : Tito_5CIY.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5CIY-query.scw PDB file : Tito_Scwrl_5CIY.pdb: