Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKKKSFSIVIAGGGST-FTPGIVLMLLDHLEEFP--IRKLKLYDNDKERQDRIAGACDVFIREKAPDIEFAATTDPEEAFTDVDFVMAHIRVG-------KYAMRALDEQIPLKYGVV----GQETCGPGGIAYGMRSIG---GVLEILDYMEKYSPDAWMLNYSNPAAIVAEATRRLRPNSKILNICDMPVGIEDRMAQILGLSSRKEMKVRYYGLNHFGWWTSIQDQEGNDLMPKLKEHVSQYGYIPKTEAEAVEASWN---DTFAKARDVQAADPDTLPN------TYLQYYLFPDDMVKKSNP-NHT-----RANE---VMEGREAFIFSQCDM----ITREQSSENSEI--KIDDHASYIVDLARAIAYNTGERMLLIVENNGAIANFDPTAMVEVPCIVGSNGPEPITVGT-IPQFQKGL-MEQQVSVEKLTVEAWAEKSFQKLWQALILSKTVPNARVARLILEDLVEANKD--FWPELDQSPTRIS 3U95 Chain:A ((1-468)) -----MKISIVGAGSVRFALQLVEDIAQTD-ELSREDTHIYLMDVHERRLNASYILARKYVEELNSPVKVVKTESLDEAIEGADFIINTAYPYDPRYHDSGSQRWDEVTKVGEKHGYYRGIDSQELNMVSTYTYVLSSYPDVKLALEIAEKMKKMAPKAYLMQTANPVFEITQAVRRW-TGANIIGFCHGVA-GVYEVFERLGLD-PEEVDWQVAGVNHGIWLNRFRY-RGKDAYPLLDEWIEKELSKWEP-----KNPWDTQMSPA--AMDMYRFYG-MLPIGDTVRNGTWKYHYNLETKKKWFRRFGGIDNEVERPKFHEHLRRARE-RLIKLAEEVQENPHLKITEKHPEIFPKGRLSGEQHIPFINAIANNKRVRLFLNVENQGALKDFPDDLVMELPVWVDSSGIHREKVEPDLTHRIKIFYLWPRILRTEWNLEAFISRDRKVLEEILIRDPRTKSYEQVVKVLDEILSLPFNEEIRRYYE-------

General information: TITO was launched using: RESULT: Template: 3U95.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2168 -235501 -108.63 -556.74 target 2D structure prediction score : 0.70 Monomeric hydrophicity matching model chain A : 0.70 3D Compatibility (PKB) : -108.63 2D Compatibility (Sec. Struct. Predict.) : 0.70 1D Compatibility (Hydrophobicity) : 0.70 QMean score : 0.416

(partial model without unconserved sides chains): PDB file : Tito_3U95.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3U95-query.scw PDB file : Tito_Scwrl_3U95.pdb: