Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNQKAVILDEQAIRRALTRIAHEMIERNKGMNNCILVGIKTRGIYLAKRLAERIEQIEGNPVTVGEIDITLYRDDLSKKTSNDEPLVKGADIPVDITDQKVILVDDVLYTGRTVRAGMDALVDVGRPSSIQLAVLVDRGHRELPIRADYIGKNIPTSKSEKVMVQLDEVDQNDLVAIYENE 1A4X Chain:B ((4-180)) ---KAVILDEQAIRRALTRIAHEMIERNKGMNNCILVGIKTRGIYLAKRLAERIEQIEGNPVTVGEIDITLY----------DEPLVKGADIPVDITDQKVILVDDVLYTGRTVRAGMDALVDVGRPSSIQLAVLVDRGHRELPIRADYIGKNIPTSKSEKVMVQLDEVDQNDLVAIYEN-

General information: TITO was launched using: RESULT: Template: 1A4X.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 924 -123659 -133.83 -740.47 target 2D structure prediction score : 0.77 Monomeric hydrophicity matching model chain B : 0.98 3D Compatibility (PKB) : -133.83 2D Compatibility (Sec. Struct. Predict.) : 0.77 1D Compatibility (Hydrophobicity) : 0.98 QMean score : 0.638

(partial model without unconserved sides chains): PDB file : Tito_1A4X.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1A4X-query.scw PDB file : Tito_Scwrl_1A4X.pdb: