Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKSLEEKTIAKEQIFSGKVIDLYVEDVELPNGKASKREIVKHPGAVAVLAVTDEGKIIMVKQFRKPLERTIVEIPAGKLEKGEEPEYTALRELEEETGYTAKKLTKITAFYTSPGFADEIVHVFLAEELSVLEEKRELDEDEFVEVMEVTLEDALKLVESREVYDAKTAYAIQYLQLKEALQAQK 5C7Q Chain:B ((3-173)) --HLEEKTLSTRQIFKGRYLKIEQDQVQAPDGRTYTREYILHPGAAMMIPLLPNGNVVMIHQYRHAVKKVFLEFPAGKRDHNEETLLTAKRELLEETGYEAKDWKFLTTIHPVIGYSNEHIDLYLARDLTHLEQR--LDQGEFIEVVEVKPADLMQLVLEGKVSDVKTQIGAFWL----------

General information: TITO was launched using: RESULT: Template: 5C7Q.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 752 -59076 -78.56 -345.47 target 2D structure prediction score : 0.48 Monomeric hydrophicity matching model chain B : 0.84 3D Compatibility (PKB) : -78.56 2D Compatibility (Sec. Struct. Predict.) : 0.48 1D Compatibility (Hydrophobicity) : 0.84 QMean score : 0.412

(partial model without unconserved sides chains): PDB file : Tito_5C7Q.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5C7Q-query.scw PDB file : Tito_Scwrl_5C7Q.pdb: