Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence --------------------MKIRGLDQFIQSLDRASRGGLKRKYEQWLE------SMGFE-FLDIIQDEIIRTKTVDTRRLLNSFQKGDQD-NIFSMTEGSLKLDVGTNLDYASYVNDGHFTI----------DPSKNQDR---RWVPGRWKG-DRFEYD-PAEKNSGMLLKFRWV---DGSGFWDNAMAIFQLMFERSLER-K-LQQWIYEEF---------- 3WOZ Chain:A ((645-869)) TEDVAEVLNRCASSNWSERKEGLLGLQNLLKNQRTLSRIELKRLCEIFTRMFADPHGKVFSMFLETLVDFIQVHKDDLQDWLFVLLTQLLKKMGADLLGSVQAKVQKALDITRESFPNDLQFNILMRFTVDQTQTPSLKVKVAILKYIETLAKQMDPRDFTNSSETRLAVSRVITWTTEPKSSDVRKAAQSVLISLFELNTPEFTMLLGALPKTFQDGATKLLHN

General information: TITO was launched using: RESULT: Template: 3WOZ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 637 23818 37.39 142.62 target 2D structure prediction score : 0.47 Monomeric hydrophicity matching model chain A : 0.63 3D Compatibility (PKB) : 37.39 2D Compatibility (Sec. Struct. Predict.) : 0.47 1D Compatibility (Hydrophobicity) : 0.63 QMean score : 0.097

(partial model without unconserved sides chains): PDB file : Tito_3WOZ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3WOZ-query.scw PDB file : Tito_Scwrl_3WOZ.pdb: