Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDLKQYVTIVPDYPKEGVQFKDITTLMDKGDVYRYATDQIVEYAKEKQIDLVVGPEARGFIIGCPVAYALGVGFAPVRKEGKLPREVIKVDYGLEYGKDVLTIHKDAIKPGQRVLITDDLLATGGTIEATIKLVEELGGVVAGIAFLIELSYLDGRNKLEDYDILTLMKY 4M0K Chain:D ((31-190)) --LKQAIRTVPDFPEPGIQFKDITPVLGHPELLRLAIEALLEPFQEQEITKVVGIESRGFILGGMLAHHLDAGFVPVRKKGKLPYQTLAESYQLEYGTDTIEMHIDAIEPGDRVLIHDDVIATGGTAEATIRLVERAGGEVVGCAFLIELTGLQGRKRLPAH--------

General information: TITO was launched using: RESULT: Template: 4M0K.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain D - contact count / total energy / energy per contact / energy per residue : 764 -120480 -157.70 -753.00 target 2D structure prediction score : 0.53 Monomeric hydrophicity matching model chain D : 0.83 3D Compatibility (PKB) : -157.70 2D Compatibility (Sec. Struct. Predict.) : 0.53 1D Compatibility (Hydrophobicity) : 0.83 QMean score : 0.549

(partial model without unconserved sides chains): PDB file : Tito_4M0K.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4M0K-query.scw PDB file : Tito_Scwrl_4M0K.pdb: