Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNINIVTIGKLKEKYLKQGIEEYTKRLSAYAKIDIIELPDEKAPENLSDQDMKIIKDKEGDRILSKISPDAHVIALAIEGKMKTSEELADTIDKLATYGKSKVTFVIGGSLGLSDTVMKRADEKLSFSKMTFPHQLMRLILVEQIYRAFRINRGEPYHK 4FAK Chain:A ((5-163)) MKITILAVGKLKEKYWKQAIAEYEKRLGPYTKIDIIEVPDEKAPENMSDKEIEQVKEKEGQRILAKIKPQSTVITLEIQGKMLSSEGLAQELNQRMTQGQSDFVFVIGGSNGLHKDVLQRSNYALSFSKMTFPHQMMRVVLIEQVYRAFKIMRGEAYHK

General information: TITO was launched using: RESULT: Template: 4FAK.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 716 -94201 -131.57 -592.46 target 2D structure prediction score : 0.76 Monomeric hydrophicity matching model chain A : 0.92 3D Compatibility (PKB) : -131.57 2D Compatibility (Sec. Struct. Predict.) : 0.76 1D Compatibility (Hydrophobicity) : 0.92 QMean score : 0.743

(partial model without unconserved sides chains): PDB file : Tito_4FAK.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4FAK-query.scw PDB file : Tito_Scwrl_4FAK.pdb: